Reports of the protein could help diagnose Alzheimers disease
Reports of the protein in the cerebrospinal fluid can help patients with a diagnosis of suspected Alzheimers disease, according to Swiss researchers. The two proteins - tau phosphorylated (phospho-tau) and beta-amyloid peptide-42 (A-beta-42) - have been linked to Alzheimers disease. But measuring levels of a protein has not been demonstrated in the diagnosis of the disease. However, Dr. Christopher Hock and staff of the University Hospital of Zurich found that the calculation of the ratio of one to another can help diagnose Alzheimers disease.The researchers determined the rate of phospho-tau to A-beta-42 100 patients for mental deterioration and a control group of 31 healthy subjects tested. 30 patients with non-related mental decline of Alzheimers disease, 19 with other
neurological diseases and 51 diagnosed with Alzheimers disease. Alzheimers protein intake was significantly higher than in all other subjects. At least 80 percent of the time of Alzheimers disease was correctly identified by the high. At least 73 percent of the time correctly identified the people without Alzheimers.Dr. Douglas Galasko of the University of California, San Diego, who conducted research in the same area of ​​medicine, described the encouraging results, but he believes that many areas of research are needed before the role of proteins in clinical practice can be established. Reference: Dr. Christoph Hock et al. Biochemical diagnosis of Alzheimers disease by measuring the ratio of phosphorylated tau protein cerebrospinal fluid amyloid peptide. Archives ofNeurology, September 2002 2003 60: 1202-1206.Order mebendazole