Scientists analyze chromosomes 2 and 4
Supported by NHGRI researchers to explore the deserts of the greatest geniuses, finding the keys to the main event of the ancestral chromosome fusion - a detailed analysis of chromosomes 2 and 4 has identified the genes known largest desert in the human genome and uncovered more evidence that human chromosome 2 was born from the fusion of two ancestral ape chromosomes, researchers supported by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), reported today.School of Medicine in St. Louis, described its analysis of the reference sequence of high quality, chromosomes 2 and 4 Stanford DNA Sequencing and Technology Development Center, Stanford, the work of sequencing chromosomes was as part of the Human Genome Project at
Washington University, Broad Institute of MIT, Cambridge, Massachusetts, performed California, Wellcome Trust Sanger Institute, Hinxton, England, National Yang -Ming University, Taipei, Taiwan, Genoscope, Evry, France, Baylor College of Medicine in Houston, University of Washington in multi-megabase Sequencing Center in Seattle, U.(DOE) Joint Genome Institute in Walnut Creek, Calif., and Roswell Park Cancer Institute, Buffalo, NY This analysis is an impressive accomplishment, deepening the knowledge of the human genome, and accelerate the discovery of genes related to human health and disease . Moreover, these results provide interesting information on the new structure and evolution of mammalian genomes, said Francis S. Collins, MD, Ph.D., director of NHGRI, which led to
the U.S. component of the Human Genome Project to the DOE.Chromosome 4 has long been interested in the medical community because it holds the gene for Huntingtons disease, polycystic kidney disease, a form of muscular dystrophy and a variety of other hereditary diseases. Chromosome 2 is noteworthy for being the second largest human chromosome, trailing only chromosome 1 in size. It is also home to the gene with the
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